Timo Glock will not contest Saturday's qualifying for the European GP due to a stomach bug.
The Marussia driver was not feeling well after arriving in Valencia but still took part in the practice sessions.
However, the German felt unwell again after Saturday's final practice and has therefore opted not to run in qualifying.
A team statement read: "Marussia F1 Team driver Timo Glock will not take part in this afternoon's Qualifying session for tomorrow's European Grand Prix for health reasons.
"Timo has been fighting a stomach bug since Thursday. He felt well enough to take part in yesterday's Free Practice sessions and had seemed to be improving. This morning, after Free Practice 3, he started to feel unwell again. It is clear that at this time, he is not sufficiently well to take part in a demanding Qualifying session and needs to recuperate further.
"Timo and the Team will now seek further medical guidance this afternoon. Until such time as this guidance has been received, no decisions will be reached regarding tomorrow's race. A further statement will be issued on Sunday morning."